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Matt Carson


Image of Matthew B. Carson, Head of the Digital Systems Department at Galter Library.Matthew B. Carson, PhD
Ward 2-321
Phone: (312) 503-5321
Email Matt
ORCiD icon GitHub icon


Matt is a trained bioinformatician with a wide range of experience in informatics and data science. He has developed, directed, and taught data science courses in the Driskill Graduate Program, the Health Sciences Integrated Program, and the Master of Science in Clinical Investigation Program. As Head of Galter's Digital Systems Department, Matt oversees the creation, development, and maintenance of the library's website, as well as the evaluation and implementation of systems that support the goals and mission of the library and Northwestern University. He leads the DataLab, a research support core that designs and develops novel, sustainable data services throughout all stages of the research data life cycle. He is the Northwestern Project Lead for InvenioRDM, a multi-site collaborative project led by CERN to build a turn-key, next-generation research data management platform. Matt also serves as the Director of Data and Technology for the NNLM National Evaluation Center (NEC).

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Recent Presentations, Abstracts, and Workshops

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Peer-reviewed Publications

  • Luo Y, Mao C, Sanchez-Pinto LN, Ahmad FS, Naidech N, Rasmussen L, Pacheco JA, Schneider D, Mithal LB, Dresden S, Holmes K, Carson MB, Shah SJ, Khan S, Clare S, Wunderink RG, Liu H, Walunas T, Cooper L, Yue F, Wehbe F, Fang D, Liebovitz DM, Markl M, Michelson KN, McColley SA, Green M, Starren J, Ackermann RT, D’Aquila RT, Adams J, Lloyd-Jones D, Chisholm RL, Kho A. Northwestern University resource and education development initiatives to advance collaborative artificial intelligence across the learning health system. Learn Health Sys. 2024; e10417. DOI: 10.1002/lrh2.10417
  • Champieux R, Solomonides A, Conte M, Rojevsky S, Phuong J, Dorr DA, Zampino E, Wilcox A, Carson MB, Holmes K. (2023) Ten simple rules for organizations to support research data sharing. PLoS Comput Biol 19(6): e1011136. doi: 10.1371/journal.pcbi.1011136.
  • Carson, M. B., Gonzales, S., Shaw, P., Schneider, D., Holmes, K. Bridging the gap: A library-based collaboration to enhance data skills for clinical researchers. Learn Health Sys. 2023; 7( 2):e10339. DOI:10.1002/lrh2.10339.
  • Gonzales, S., Carson, M. B., Holmes, K. Ten Simple Rules for Maximizing the Recommendations of the NIH Data Management and Sharing Plan. PLoS Comput Biol. 2022;18(8): e1010397.
  • Gonzales, S., Carson, M. B., Viger, G., O’Keefe, L., Allen, N. B., Ferrie, J. P., Holmes, K. User Testing with Microinteractions. Information Technology and Libraries. 2021. 40(1), doi: 10.6017/ital.v40i1.12341.
  • Chandler, A. E., Mutharasan, R.K., Amelia, L., Carson, M. B., Scholtens, D. M., Soulakis, N. D. Methods of Information in Medicine 58(2-3):71-78 01 Jan 2019, doi: 10.1055/s-0039-1694990.
  • Jia, C., Carson, M. B., Wang, X., Yu, J. Concept Decompositions for Short Text Clustering by Identifying Word Communities, Pattern Recognition (2017), doi: 10.1016/j.patcog.2017.09.045.
  • Luo, Y., Thompson, W. K., Herr, T. M., Zeng, Z., Berendsen, M. A., Jonnalagadda, S. R., Carson, M. B., Starren, J. Natural Language Processing for EHR-Based Pharmacovigilance: A Structured Review. Drug Saf. 2017 Jun 22. doi: 10.1007/s40264-017-0558-6. [Epub ahead of print]. PMID: 28643174
  • Jia, C., Li, Y., Carson, M. B., Wang, X., and Yu, J. Node Attribute-enhanced Community Detection in Complex Networks. Scientific Reports. 2017, 7 (2626). doi: 10.1038/s41598-017-02751-8. PMID: 28572625
  • Carson, M. B., Liu, C., Lu, Y., Jia, C., and Lu, H. A Disease Similarity Matrix based on the Uniqueness of Shared Genes. BMC Medical Genomics 2017, 10(Suppl 1):26.
    doi: 10.1186/s12920-017-0265-2. PMID: 28589854
  • Carson, M. B., Scholtens, D. M., Frailey, C. N., Gravenor, S. J., Powell, E. S., Wang, A. Y., Kricke, G. S., Ahmad, F. S., Mutharasan, R. K., and Soulakis, N. D. Characterizing Teamwork in Cardiovascular Care Outcomes: A Network Analytics Approach. Circ Cardiovasc Qual Outcomes. 2016 Nov; 9(6): 670–678. doi: 10.1161/CIRCOUTCOMES.116.003041. PMID: 28051772
  • Carson, M. B., Gravenor, S. J., Scholtens, D. M., Frailey, C. N., Kricke, G. S., and Soulakis, N. D. An outcome-weighted network model for characterizing collaboration. PLoS ONE. 2016 Oct 5. doi: 10.1371/journal.pone.0163861. PMID: 27706199
  • Kricke, G. S., Carson, M. B., Lee, Y., Benacka, C., and Soulakis, N. D. Leveraging Electronic Health Record Documentation for Failure Mode and Effects Analysis Team Identification on an Inpatient Cardiology Unit. J Am Med Inform Assoc. 2016 Sep 1. pii: ocw083. doi: 10.1093/jamia/ocw083. PMID: 27589944
  • Qin, W., Zhao, G., Carson, M. B., Jia, C., and Lu, H. Knowledge-based three-body potential for transcription factor binding site prediction. IET Syst. Biol. 2016 Feb;10(1):23-9. doi: 10.1049/iet-syb.2014.0066. PMID: 26816396
  • Carson, M. B., Gu, J., Yu, G., and Lu, H. Identification of Cancer-related Genes and Motifs in the Human Gene Regulatory Network. IET Syst. Biol. 2015, Aug;9(4):128-34. doi: 10.1049/iet-syb.2014.0058. PMID: 26243828
  • Carson, M. B. and Lu, H. Network-based Prediction and Knowledge Mining Of Disease Genes. BMC Medical Genomics 2015, 8 (Suppl 2):S9. doi: 10.1186/1755-8794-8-S2-S9. PMID: 26043920
  • Soulakis, N., Carson, M. B., Lee, Y. J., Schneider, D. H., Skeehan, C. T., and Scholtens, D. M. Visualization of multidisciplinary, collaborative care for hospitalized heart failure patients. J Am Med Inform Assoc, Special Issue on Visual Analytics in Healthcare. 2015 Feb 20. doi:10.1093/jamia/ocu017. PMID: 25710558
  • Jia, C., Carson, M. B., Wang, Y., Lin, Y., and Lu, H. A New Exhaustive Method and Strategy for Finding Motifs in ChIP-enriched Regions. PLoS ONE. 2014, 9(1): e86044. PMID: 24475069
  • Lu, Y., Deng, J., Carson, M. B., Lu, H., and Lu, L. J. Computational methods for the prediction of microbial essential genes. Current Bioinformatics. 2013, 9(2):89-101.
  • Jia, C., Carson, M. B., and Yu, J. A Fast Weak Motif-Finding Algorithm Based on Community Detection in Graphs. BMC Bioinf. 2013, 14:227. doi:10.1186/1471-2105-14-227. PMID: 23865838
  • Siddaramappa, S., Challacombe, J. F., Duncan, A. J., Gillaspy, A. F., Carson, M. B., Gipson, J., Orvis, J., Zaitshik, J., Barnes, G., Bruce, D., Chertkov, O., Detter, J. C., Han, C. S., Tapia, R., Thompson, L. S., Dyer, D. W., and Inzana, T. J. Horizontal gene transfer in Histophilus somni and its role in the evolution of pathogenic strain 2336, as determined by comparative genomic analyses. BMC Genomics. 2011 Nov 23;12:570. doi:10.1186/1471-2164-12-570. PMID: 22111657
  • Carson, M. B., Langlois, R., and Lu, H. NAPS: A Residue-level Nucleic Acid-binding Prediction Server. Nucleic Acids Res. 2010. Jul; 38 (Web Server issue):W431-5. doi:10.1093/nar/gkq361. PMID: 20478832
  • Bhardwaj, N., Carson, M. B., Abyzov, A., Yan, K., Lu, H., and Gerstein, M. B. Analysis of Combinatorial Regulation: Scaling of Partnerships between Regulators with the Number of Governed Targets. PLoS Comput. Biol. 2010 May 27; 6(5): e1000755. doi:10.1371/journal.pcbi.1000755. PMID: 20523742
  • Carson, M. B., Langlois, R., and Lu, H. Mining Knowledge for the Methylation Status of CpG Islands Using Alternating Decision Trees, Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE, 20-25 Aug. 2008 Page(s):3787–3790. PMID: 19163536
  • Zhao, G., Carson, M. B., and Lu, H.  Prediction of specific protein-DNA recognition by knowledge-based two-body and three-body interaction potentials. Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE, 22-26 Aug. 2007 Page(s):5017-5020. PMID: 18003133
  • Langlois, R. E., Carson, M. B., Bhardwaj, N., and Lu, H.  Learning to translate sequence and structure to function: identifying DNA-binding and membrane binding proteins.  Annals of Biomedical Engineering.  2007 Jun; 35(6):1043-1052. PMID: 17436108
  • Harrison, A., Dyer, D. W., Gillaspy, A. F., Ray, W. C., Mungur, R., Carson, M. B., Gipson, J., Gipson, M., Johnson, L. S., Lewis, L., Bakaletz, L. O., and Munson, R. S. Jr. Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae:  a comparative study with Haemophilus influenzae serotype d, strain KW20.  J. Bacteriol. 2005 Jul;187(13):4627-36.  PMID: 15968074
  • Ducey, T. F., Carson, M. B., Orvis, J., Stintzi, A. P., and Dyer, D. W. Identification of the Iron-Responsive Genes of Neisseria gonorrhoeae by Iron-limitation Gene Analysis in Defined Medium.  J. Bacteriol. 2005 Jul;187(14):4865-74. PMID: 15995201
  • Munson, R. S. Jr., Harrison, A., Gillaspy, A., Ray, W. C., Carson, M. B., Armbruster, D., Gipson, J., Gipson, M., Johnson, L., Lewis, L., Dyer, D. W., and Bakaletz L. O.  Partial analysis of the genomes of two nontypeable Haemophilus influenzae otitis media isolates.  Infect Immun.  2004 May; 72(5):3002-10. PMID: 15102813
  • Ajdic, D., McShan, W. M., McLaughlin, R. E., Savic, G., Chang J., Carson, M. B., Primeaux, C., Tian, R., Kenton, S., Jia, H., Lin, S., Qian, Y., Li, S., Zhu, H., Najar, F., Lai, H., White, J., Roe, B. A., and Ferretti. J. J. Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen.  Proc Natl Acad Sci USA.  2002 Oct 29; 99(22):14434-9.  Epub 2002 Oct 23.  PMID: 12397186
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Updated: May 16, 2024